Proteomics throughput is increasing, driven by advances in resolution, cost, and speed. Manual pipetting during sample preparation not only wastes time, but has become a bottleneck limiting research, leading labs all over the world to embrace automation.
Dr. Joao Paulo, PhD, and his laboratory at the Harvard Medical School Department of Cell Biology employ mass spectrometry-based proteomics (MSP) analysis to better understand the effects of molecular mechanisms and cell signaling pathways on the regulation of the proteome of various model systems.
Join for a demonstration of how the Opentrons Flex and its modules automate complex proteomics tasks, and get tips on how your day-to-day protein sample processing work can be seamlessly performed on the platform
With the Flex Magnetic Bead Protein Purification Workstation, you can automate your bead-based protein purification workflow at the scale you need to increase efficiency, reduce errors, and save hands-on time. Flex enables you to automate small-scale isolation of specific proteins, protein complexes, and antibodies, or proteomics sample processing, using many leading magnetic bead-based reagent systems on the market.
Save time by downloading free protocols from the Opentrons Protocol Library. Select from a range of protein extraction (including SP3), quantification, and proteomic sample preparation methods including digestion and normalization.
An end-to-end solution that provides a cost-effective workflow for high-throughput sample processing, encompassing protein concentration determination and sample digestion.
Automation of three ELISA protocols on the Opentrons OT-2 with an on-deck Heater-Shaker Module
Automation of bead-based ELISA forSARS-CoV-2 neutralizing antibody on the Opentrons OT-2 with an on-deck Heater-Shaker Module
Automated Protein Purification with Biotage Dual Flow Chromatography PhyTip Columns on the OT-2
Automated Ni-NTA bead-based protein purification on the OT-2 liquid handler
A Semiautomated Paramagnetic Bead-Based Platform For Isobaric Tag Sample Preparation